| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 8,851 | 8,901 | 18,116 | |
| 2020 | D | 10,299 | 9,004 | 19,757 | |
| 2016 | D | 8,859 | 8,576 | 18,124 | |
| 2012 | D | 9,095 | 8,761 | 18,117 | |
| 2008 | D | 9,326 | 9,320 | 18,792 | |
| 2004 | R | 7,015 | 9,068 | 16,290 | |
| 2000 | R | 6,443 | 7,959 | 14,804 | |
| 1996 | R | 5,923 | 6,142 | 12,524 | |
| 1992 | R | 5,726 | 6,381 | 13,156 | |
| 1988 | R | 5,100 | 7,126 | 12,289 | |
| 1984 | R | 5,097 | 7,574 | 12,697 | |
| 1980 | R | 6,039 | 6,300 | 12,675 | |
| 1976 | R | 4,339 | 5,194 | 9,725 | |
| 1972 | R | 1,880 | 6,160 | 8,153 | |
| 1968 | D | 1,826 | 1,276 | 7,229 | |
| 1964 | R | 390 | 3,795 | 4,185 | |
| 1960 | D | 915 | 829 | 3,416 | |
| 1956 | D | 1,552 | 702 | 2,640 | |
| 1952 | D | 1,666 | 1,435 | 3,101 | |
| 1948 | D | 158 | 58 | 2,004 | |
| 1944 | D | 1,948 | 110 | 2,058 | |
| 1940 | D | 1,951 | 79 | 2,044 | |
| 1936 | D | 1,714 | 19 | 1,734 | |
| 1932 | D | 1,574 | 26 | 1,600 | |
| 1928 | D | 1,577 | 111 | 1,688 | |
| 1924 | D | 1,370 | 30 | 1,442 | |
| 1920 | D | 778 | 70 | 849 | |
| 1916 | D | 911 | 48 | 960 | |
| 1912 | D | 851 | 30 | 912 | |
| 1908 | — | — | — | — | |
| 1904 | — | — | — | — | |
| 1900 | D | 663 | 14 | 689 | |
| 1896 | D | 816 | 27 | 849 | |
| 1892 | D | 595 | 0 | 629 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Home to Mississippi State University, Oktibbeha County's large student and faculty population pulls it toward statewide competitiveness in a way few rural Mississippi counties can match, making it a reliable bellwether for university-anchored demographics.
The county's recent history is a story of close margins. The Democratic margin reached ninety-eight points in 1936; the Republican margin reached eighty-one points in 1964. Most other elections have been decided by single-digit points.
Oktibbeha County's demographics — a population of 51,771, a 55% non-Hispanic-white share, a median household income of $46,695 — situate the county close to national averages on several dimensions. The county's voting pattern over the last decade is most similar to that of Chesapeake city and Duval County.