| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 2,214 | 11,740 | 14,068 | |
| 2020 | R | 2,614 | 11,550 | 14,361 | |
| 2016 | R | 2,386 | 10,336 | 12,984 | |
| 2012 | R | 2,804 | 9,448 | 12,411 | |
| 2008 | R | 2,982 | 9,727 | 12,868 | |
| 2004 | R | 2,660 | 8,480 | 11,240 | |
| 2000 | R | 2,771 | 6,601 | 9,510 | |
| 1996 | R | 2,597 | 4,289 | 7,709 | |
| 1992 | R | 2,965 | 4,595 | 8,366 | |
| 1988 | R | 2,772 | 4,939 | 7,740 | |
| 1984 | R | 2,434 | 5,182 | 7,643 | |
| 1980 | D | 4,499 | 3,198 | 7,802 | |
| 1976 | D | 4,066 | 2,245 | 6,491 | |
| 1972 | R | 488 | 4,476 | 5,004 | |
| 1968 | R | 599 | 733 | 6,130 | |
| 1964 | R | 702 | 2,699 | 3,401 | |
| 1960 | D | 1,584 | 328 | 2,704 | |
| 1956 | D | 2,320 | 335 | 2,812 | |
| 1952 | D | 2,281 | 648 | 2,929 | |
| 1948 | D | 348 | 28 | 1,915 | |
| 1944 | D | 1,716 | 87 | 1,803 | |
| 1940 | D | 2,171 | 70 | 2,244 | |
| 1936 | D | 2,286 | 93 | 2,388 | |
| 1932 | D | 1,862 | 31 | 1,900 | |
| 1928 | D | 1,537 | 261 | 1,798 | |
| 1924 | D | 1,206 | 86 | 1,292 | |
| 1920 | D | 992 | 439 | 1,448 | |
| 1916 | D | 1,314 | 110 | 1,427 | |
| 1912 | D | 1,009 | 47 | 1,181 | |
| 1908 | — | — | — | — | |
| 1904 | — | — | — | — | |
| 1900 | D | 732 | 182 | 972 | |
| 1896 | D | 944 | 64 | 1,023 | |
| 1892 | D | 461 | 9 | 922 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Pontotoc County, in Mississippi's hill country northeast of the Delta, recorded an R+67.7 presidential margin in 2024—among the widest in the state—reflecting the deep rural realignment that has reshaped small-county voting across the South over the past two decades.
The unraveling was not abrupt. The Democratic margin in Pontotoc County peaked at ninety-six points in 1932; it narrowed steadily over the late twentieth century. The 1984 election delivered the county to the Republican party for the first time in many years, by a margin of thirty-six points. By 2024, the margin had widened further.
The economic and demographic context is severe. Pontotoc County's median household income of $51,484 is among the lowest of any county in the United States; 17% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Webster County and Alfalfa County.