| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | D | 2,443 | 990 | 3,468 | |
| 2020 | D | 3,016 | 1,118 | 4,189 | |
| 2016 | D | 3,071 | 1,151 | 4,253 | |
| 2012 | D | 3,903 | 1,293 | 5,212 | |
| 2008 | D | 3,634 | 1,462 | 5,126 | |
| 2004 | D | 3,168 | 1,679 | 4,900 | |
| 2000 | D | 2,288 | 1,628 | 3,944 | |
| 1996 | D | 2,305 | 1,382 | 3,813 | |
| 1992 | D | 2,696 | 1,721 | 4,683 | |
| 1988 | D | 2,644 | 2,018 | 4,695 | |
| 1984 | D | 2,596 | 2,309 | 4,914 | |
| 1980 | D | 2,970 | 1,841 | 5,020 | |
| 1976 | D | 2,172 | 1,445 | 3,774 | |
| 1972 | R | 892 | 2,334 | 3,382 | |
| 1968 | D | 1,219 | 258 | 3,628 | |
| 1964 | R | 84 | 1,863 | 1,947 | |
| 1960 | D | 459 | 231 | 1,422 | |
| 1956 | D | 576 | 127 | 1,294 | |
| 1952 | D | 858 | 589 | 1,447 | |
| 1948 | D | 17 | 11 | 1,144 | |
| 1944 | D | 1,150 | 35 | 1,185 | |
| 1940 | D | 1,061 | 20 | 1,081 | |
| 1936 | D | 1,164 | 7 | 1,171 | |
| 1932 | D | 775 | 10 | 785 | |
| 1928 | D | 1,020 | 1 | 1,021 | |
| 1924 | D | 628 | 33 | 661 | |
| 1920 | D | 316 | 21 | 339 | |
| 1916 | — | — | — | — | |
| 1912 | — | — | — | — | |
| 1908 | — | — | — | — | |
| 1904 | — | — | — | — | |
| 1900 | — | — | — | — | |
| 1896 | — | — | — | — | |
| 1892 | — | — | — | — | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Humphreys County in the Mississippi Delta posts some of the widest Democratic presidential margins in the state, driven by a majority-Black population shaped by the region's cotton agriculture history and persistent rural poverty.
The unraveling was not abrupt. The Democratic margin in Humphreys County peaked at 100 points in 1928; it narrowed steadily over the late twentieth century. The 1976 election delivered the county to the Republican party for the first time in many years, by a margin of nineteen points. By 2024, the margin had widened further.
The economic and demographic context is severe. Humphreys County's median household income of $33,731 is among the lowest of any county in the United States; 27% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Coahoma County and Dallas County.