| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 3,510 | 6,487 | 10,205 | |
| 2020 | R | 3,517 | 6,143 | 9,996 | |
| 2016 | R | 3,098 | 5,406 | 9,182 | |
| 2012 | R | 4,149 | 4,530 | 8,955 | |
| 2008 | R | 4,430 | 4,785 | 9,434 | |
| 2004 | R | 4,409 | 5,299 | 9,940 | |
| 2000 | R | 3,745 | 4,845 | 9,256 | |
| 1996 | D | 4,343 | 2,815 | 8,920 | |
| 1992 | D | 3,323 | 2,970 | 10,031 | |
| 1988 | R | 3,323 | 4,788 | 8,217 | |
| 1984 | R | 3,016 | 5,427 | 8,482 | |
| 1980 | R | 3,550 | 4,015 | 8,555 | |
| 1976 | R | 3,727 | 4,084 | 8,090 | |
| 1972 | R | 2,518 | 4,617 | 7,136 | |
| 1968 | D | 3,561 | 3,199 | 6,918 | |
| 1964 | D | 4,781 | 2,473 | 7,261 | |
| 1960 | R | 2,859 | 4,959 | 7,818 | |
| 1956 | R | 1,541 | 5,336 | 6,877 | |
| 1952 | R | 2,261 | 4,652 | 6,923 | |
| 1948 | R | 2,181 | 3,227 | 5,438 | |
| 1944 | R | 2,957 | 3,536 | 6,494 | |
| 1940 | R | 3,499 | 3,806 | 7,312 | |
| 1936 | R | 3,051 | 4,057 | 7,295 | |
| 1932 | R | 2,849 | 4,198 | 7,099 | |
| 1928 | R | 1,353 | 4,792 | 6,161 | |
| 1924 | R | 974 | 4,031 | 5,308 | |
| 1920 | R | 1,788 | 4,049 | 5,886 | |
| 1916 | R | 1,763 | 2,142 | 3,955 | |
| 1912 | D | 1,210 | 807 | 3,770 | |
| 1908 | R | 828 | 2,157 | 3,060 | |
| 1904 | R | 616 | 2,043 | 2,742 | |
| 1900 | R | 824 | 2,023 | 2,997 | |
| 1896 | R | 904 | 2,342 | 3,328 | |
| 1892 | R | 1,249 | 1,909 | 3,290 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Piscataquis covers more than 4,300 square miles yet holds fewer than 17,500 residents, making it one of the least dense counties east of the Mississippi. That rural isolation tracks closely with its consistent and widening Republican margins at the presidential level.
The Republican margin in Piscataquis County reached its widest at fifty-eight points in 1924. The margin in 2024 was twenty-nine points, in line with the county's deep historical pattern.
Piscataquis County's loyalty is rooted in its place. Median household income of $61,345, a 93% non-Hispanic-white share, and a population of 17,263 together describe a community whose political habits are deeply settled. The county's voting pattern over the last decade is most similar to that of Chippewa County and Jefferson County.