| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 3,388 | 5,465 | 8,912 | |
| 2020 | R | 4,022 | 5,594 | 9,668 | |
| 2016 | R | 3,972 | 5,456 | 9,477 | |
| 2012 | R | 4,455 | 5,124 | 9,611 | |
| 2008 | R | 4,594 | 5,434 | 10,067 | |
| 2004 | R | 3,915 | 5,170 | 9,132 | |
| 2000 | R | 4,143 | 4,306 | 8,540 | |
| 1996 | D | 4,018 | 3,322 | 7,773 | |
| 1992 | D | 3,783 | 3,634 | 8,142 | |
| 1988 | R | 3,107 | 3,851 | 6,982 | |
| 1984 | R | 3,586 | 4,685 | 8,296 | |
| 1980 | D | 4,504 | 3,582 | 8,182 | |
| 1976 | D | 3,776 | 2,969 | 6,786 | |
| 1972 | R | 1,933 | 4,071 | 6,046 | |
| 1968 | D | 1,434 | 321 | 6,328 | |
| 1964 | R | 0 | 3,416 | 4,162 | |
| 1960 | D | 1,836 | 1,277 | 3,156 | |
| 1956 | D | 1,660 | 993 | 2,824 | |
| 1952 | D | 1,519 | 905 | 2,442 | |
| 1948 | R | 0 | 91 | 1,524 | |
| 1944 | D | 1,482 | 209 | 1,699 | |
| 1940 | D | 1,714 | 140 | 1,863 | |
| 1936 | D | 1,665 | 107 | 1,779 | |
| 1932 | D | 1,479 | 128 | 1,698 | |
| 1928 | D | 1,028 | 634 | 1,662 | |
| 1924 | D | 1,045 | 132 | 1,195 | |
| 1920 | D | 1,419 | 263 | 1,702 | |
| 1916 | D | 1,179 | 218 | 1,419 | |
| 1912 | D | 815 | 22 | 926 | |
| 1908 | D | 816 | 69 | 956 | |
| 1904 | D | 866 | 105 | 1,062 | |
| 1900 | D | 797 | 203 | 1,127 | |
| 1896 | D | 2,210 | 211 | 2,504 | |
| 1892 | D | 1,919 | 83 | 3,018 | |
| 1888 | D | 1,326 | 17 | 1,344 | |
| 1884 | D | 1,085 | 31 | 1,123 | |
| 1880 | D | 1,562 | 214 | 1,776 | |
| 1876 | D | 2,158 | 48 | 2,206 |
Pickens sits on Alabama's Black Belt fringe, where a majority-Black population and declining rural economy have produced shifting but persistently lopsided presidential results — the 2024 margin of R+23.3 continues a decade-long trend away from its historic Democratic lean.
The shift began with civil rights. 2000 marked the realignment in Pickens County, by a two points margin. The Republican margin reached its widest at eighty-two points in 1964. The 2024 margin was twenty-three points.
The political shift has tracked, in Pickens County, the political shift of the South more broadly. A 56% non-Hispanic-white share, a median household income of $46,274, and a 20% poverty rate describe the demographic context. The county's voting pattern over the last decade is most similar to that of Brooks County and Coosa County.
