| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 1,553 | 11,358 | 13,006 | |
| 2020 | R | 1,624 | 10,583 | 12,301 | |
| 2016 | R | 1,547 | 8,953 | 10,647 | |
| 2012 | R | 2,132 | 7,506 | 9,779 | |
| 2008 | R | 2,306 | 7,298 | 9,745 | |
| 2004 | R | 3,040 | 5,923 | 9,049 | |
| 2000 | R | 3,497 | 4,154 | 7,823 | |
| 1996 | D | 4,399 | 3,048 | 8,421 | |
| 1992 | D | 4,222 | 2,745 | 7,876 | |
| 1988 | D | 3,176 | 2,868 | 6,101 | |
| 1984 | R | 3,029 | 3,225 | 6,319 | |
| 1980 | D | 3,764 | 2,482 | 6,438 | |
| 1976 | D | 4,668 | 1,492 | 6,256 | |
| 1972 | R | 1,182 | 3,179 | 4,422 | |
| 1968 | D | 462 | 343 | 5,685 | |
| 1964 | R | 0 | 1,893 | 3,809 | |
| 1960 | D | 3,097 | 872 | 3,973 | |
| 1956 | D | 2,661 | 845 | 3,513 | |
| 1952 | D | 2,664 | 539 | 3,211 | |
| 1948 | R | 0 | 217 | 1,293 | |
| 1944 | D | 1,774 | 408 | 2,200 | |
| 1940 | D | 2,617 | 381 | 3,010 | |
| 1936 | D | 2,113 | 375 | 2,507 | |
| 1932 | D | 1,897 | 359 | 2,283 | |
| 1928 | R | 894 | 1,515 | 2,413 | |
| 1924 | D | 1,380 | 845 | 2,276 | |
| 1920 | D | 1,969 | 1,576 | 3,603 | |
| 1916 | D | 1,136 | 508 | 1,676 | |
| 1912 | D | 814 | 88 | 1,748 | |
| 1908 | D | 712 | 602 | 1,412 | |
| 1904 | D | 905 | 502 | 1,692 | |
| 1900 | R | 1,167 | 1,169 | 2,787 | |
| 1896 | D | 1,776 | 602 | 2,485 | |
| 1892 | D | 1,709 | 139 | 3,151 | |
| 1888 | D | 1,686 | 333 | 2,040 | |
| 1884 | D | 1,397 | 427 | 1,824 | |
| 1880 | D | 1,390 | 180 | 1,570 | |
| 1876 | D | 1,666 | 293 | 1,959 |
Cherokee County's R+75.4 margin in 2024 places it among the most heavily one-sided counties in the state, a pattern consistent with the rural, predominantly white Appalachian foothills region it occupies in northeastern Alabama.
The unraveling was not abrupt. The Democratic margin in Cherokee County peaked at seventy-seven points in 1880; it narrowed steadily over the late twentieth century. The 2000 election delivered the county to the Republican party for the first time in many years, by a margin of eight points. By 2024, the margin had widened further.
The economic and demographic context is severe. Cherokee County's median household income of $53,863 is among the lowest of any county in the United States; 15% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Pittsburg County and Walker County.
