| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 20,146 | 33,623 | 54,427 | |
| 2020 | R | 18,937 | 30,312 | 49,868 | |
| 2016 | R | 13,812 | 23,719 | 38,938 | |
| 2012 | R | 13,419 | 19,333 | 33,144 | |
| 2008 | R | 12,139 | 16,441 | 28,921 | |
| 2004 | R | 7,631 | 12,916 | 20,814 | |
| 2000 | R | 8,782 | 11,676 | 20,705 | |
| 1996 | D | 8,752 | 7,544 | 17,957 | |
| 1992 | D | 8,307 | 7,757 | 18,655 | |
| 1988 | R | 6,181 | 9,152 | 15,393 | |
| 1984 | R | 5,804 | 10,383 | 16,244 | |
| 1980 | D | 8,283 | 6,410 | 15,170 | |
| 1976 | D | 8,324 | 4,997 | 13,385 | |
| 1972 | R | 2,461 | 9,016 | 11,580 | |
| 1968 | R | 3,151 | 4,874 | 12,911 | |
| 1964 | D | 4,970 | 4,742 | 9,712 | |
| 1960 | D | 5,561 | 2,909 | 8,470 | |
| 1956 | D | 4,398 | 1,610 | 6,637 | |
| 1952 | D | 4,989 | 3,080 | 8,069 | |
| 1948 | D | 855 | 30 | 2,534 | |
| 1944 | D | 2,383 | 13 | 2,536 | |
| 1940 | D | 3,205 | 14 | 3,219 | |
| 1936 | D | 2,631 | 0 | 2,631 | |
| 1932 | D | 3,103 | 0 | 3,108 | |
| 1928 | D | 1,436 | 8 | 1,444 | |
| 1924 | D | 1,355 | 8 | 1,363 | |
| 1920 | D | 1,633 | 10 | 1,643 | |
| 1916 | D | 1,426 | 1 | 1,428 | |
| 1912 | D | 1,140 | 0 | 1,151 | |
| 1908 | D | 1,730 | 58 | 1,790 | |
| 1904 | D | 1,504 | 69 | 1,573 | |
| 1900 | D | 1,300 | 70 | 1,370 | |
| 1896 | D | 1,557 | 177 | 1,734 | |
| 1892 | D | 1,744 | 624 | 2,492 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Lancaster sits in South Carolina's fast-growing Piedmont corridor, where exurban expansion from the Charlotte metro has reinforced an already strong Republican lean, producing a 24.8-point margin in 2024.
The shift began with civil rights. 2000 marked the realignment in Lancaster County, by a fourteen points margin. The Republican margin reached its widest at fifty-seven points in 1972. The 2024 margin was twenty-five points.
The political shift has tracked, in Lancaster County, the political shift of the South more broadly. A 69% non-Hispanic-white share, a median household income of $78,869, and a 11% poverty rate describe the demographic context. The county's voting pattern over the last decade is most similar to that of Floyd County and Miller County.
