| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 872 | 3,565 | 4,486 | |
| 2020 | R | 984 | 3,553 | 4,619 | |
| 2016 | R | 934 | 3,344 | 4,480 | |
| 2012 | R | 1,508 | 2,677 | 4,279 | |
| 2008 | R | 1,837 | 2,594 | 4,502 | |
| 2004 | R | 1,754 | 2,862 | 4,644 | |
| 2000 | R | 2,023 | 2,388 | 4,484 | |
| 1996 | D | 2,050 | 1,453 | 4,176 | |
| 1992 | D | 2,196 | 1,461 | 4,562 | |
| 1988 | D | 2,460 | 1,803 | 4,273 | |
| 1984 | R | 1,977 | 2,438 | 4,415 | |
| 1980 | R | 2,314 | 2,350 | 4,789 | |
| 1976 | D | 2,486 | 1,983 | 4,497 | |
| 1972 | R | 1,695 | 2,738 | 4,433 | |
| 1968 | D | 2,067 | 2,038 | 4,642 | |
| 1964 | D | 3,281 | 1,239 | 4,520 | |
| 1960 | D | 2,726 | 2,560 | 5,286 | |
| 1956 | D | 2,728 | 2,301 | 5,029 | |
| 1952 | D | 2,896 | 2,416 | 5,320 | |
| 1948 | D | 3,155 | 1,564 | 4,731 | |
| 1944 | D | 2,883 | 1,988 | 4,882 | |
| 1940 | D | 3,484 | 2,428 | 5,942 | |
| 1936 | D | 3,859 | 1,994 | 5,903 | |
| 1932 | D | 3,746 | 1,341 | 5,143 | |
| 1928 | D | 2,882 | 2,741 | 5,646 | |
| 1924 | D | 3,481 | 2,416 | 6,120 | |
| 1920 | D | 3,542 | 2,810 | 6,405 | |
| 1916 | D | 2,357 | 1,429 | 3,833 | |
| 1912 | D | 2,340 | 1,004 | 3,758 | |
| 1908 | D | 2,439 | 1,473 | 3,993 | |
| 1904 | D | 2,202 | 1,467 | 3,754 | |
| 1900 | D | 2,583 | 1,442 | 4,112 | |
| 1896 | D | 2,624 | 1,581 | 4,241 | |
| 1892 | D | 2,220 | 1,322 | 3,725 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Lewis County, tucked along the Mississippi River in northeast Missouri, recorded a 60-point Republican presidential margin in 2024 — a figure that reflects the broader rural realignment reshaping small agricultural counties across the state.
The unraveling was not abrupt. The Democratic margin in Lewis County peaked at forty-seven points in 1932; it narrowed steadily over the late twentieth century. The 2000 election delivered the county to the Republican party for the first time in many years, by a margin of eight points. By 2024, the margin had widened further.
The economic and demographic context is severe. Lewis County's median household income of $59,934 is among the lowest of any county in the United States; 13% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Monroe County and Isanti County.