| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 2,853 | 7,364 | 10,442 | |
| 2020 | R | 3,213 | 7,357 | 10,769 | |
| 2016 | R | 2,861 | 6,572 | 10,048 | |
| 2012 | R | 4,026 | 5,515 | 9,744 | |
| 2008 | D | 5,039 | 5,001 | 10,181 | |
| 2004 | R | 3,920 | 5,934 | 9,924 | |
| 2000 | R | 3,752 | 5,096 | 8,987 | |
| 1996 | D | 4,058 | 3,770 | 8,620 | |
| 1992 | D | 4,301 | 3,789 | 9,579 | |
| 1988 | R | 4,061 | 4,964 | 9,055 | |
| 1984 | R | 4,005 | 5,816 | 9,846 | |
| 1980 | R | 4,153 | 5,284 | 9,705 | |
| 1976 | D | 4,796 | 4,166 | 8,990 | |
| 1972 | R | 3,867 | 5,518 | 9,415 | |
| 1968 | R | 3,767 | 4,603 | 8,993 | |
| 1964 | D | 4,834 | 3,980 | 8,834 | |
| 1960 | R | 4,303 | 5,050 | 9,373 | |
| 1956 | R | 3,530 | 5,404 | 8,960 | |
| 1952 | R | 3,401 | 5,497 | 8,941 | |
| 1948 | R | 4,163 | 4,496 | 8,726 | |
| 1944 | R | 3,647 | 4,986 | 8,686 | |
| 1940 | R | 4,180 | 5,667 | 9,889 | |
| 1936 | D | 4,966 | 4,567 | 9,676 | |
| 1932 | D | 5,422 | 4,014 | 9,503 | |
| 1928 | R | 4,152 | 4,672 | 8,844 | |
| 1924 | D | 4,409 | 4,395 | 9,045 | |
| 1920 | R | 3,855 | 5,270 | 9,240 | |
| 1916 | R | 2,335 | 2,560 | 5,085 | |
| 1912 | D | 2,428 | 1,268 | 5,112 | |
| 1908 | R | 2,662 | 2,920 | 5,666 | |
| 1904 | R | 2,495 | 3,017 | 5,632 | |
| 1900 | R | 2,816 | 2,979 | 5,893 | |
| 1896 | R | 2,745 | 3,047 | 5,822 | |
| 1892 | D | 2,496 | 2,478 | 5,167 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Spencer County, tucked along the Ohio River in southwestern Indiana, delivers Republican presidential margins exceeding 40 points, reflecting the deep realignment of small-town and agricultural communities that has reshaped the region over the past two decades.
The Republican margin in Spencer County reached its widest at forty-three points in 2024. The margin in 2024 was forty-three points, in line with the county's deep historical pattern.
Spencer County's loyalty is rooted in its place. Median household income of $74,506, a 94% non-Hispanic-white share, and a population of 19,955 together describe a community whose political habits are deeply settled. The county's voting pattern over the last decade is most similar to that of Marshall County and Schuyler County.