| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 2,970 | 5,549 | 8,683 | |
| 2020 | R | 3,203 | 5,345 | 8,722 | |
| 2016 | R | 3,062 | 4,556 | 8,092 | |
| 2012 | D | 4,316 | 3,403 | 7,875 | |
| 2008 | D | 5,141 | 3,202 | 8,490 | |
| 2004 | R | 4,131 | 4,137 | 8,315 | |
| 2000 | D | 3,823 | 3,461 | 7,387 | |
| 1996 | D | 4,427 | 2,554 | 7,930 | |
| 1992 | D | 4,829 | 2,973 | 9,382 | |
| 1988 | D | 4,804 | 4,720 | 9,580 | |
| 1984 | R | 4,760 | 4,785 | 9,588 | |
| 1980 | D | 4,540 | 4,350 | 9,468 | |
| 1976 | D | 5,620 | 4,088 | 9,746 | |
| 1972 | R | 4,277 | 5,204 | 9,510 | |
| 1968 | D | 4,343 | 4,211 | 9,108 | |
| 1964 | D | 6,226 | 3,090 | 9,341 | |
| 1960 | D | 4,920 | 4,372 | 9,308 | |
| 1956 | R | 4,037 | 4,946 | 8,993 | |
| 1952 | R | 4,001 | 4,816 | 8,832 | |
| 1948 | D | 4,569 | 3,761 | 8,354 | |
| 1944 | R | 3,996 | 4,087 | 8,102 | |
| 1940 | R | 4,475 | 4,489 | 8,978 | |
| 1936 | D | 4,752 | 3,619 | 8,619 | |
| 1932 | D | 5,053 | 3,253 | 8,357 | |
| 1928 | D | 3,782 | 3,772 | 7,561 | |
| 1924 | D | 3,895 | 3,240 | 7,314 | |
| 1920 | R | 3,560 | 3,864 | 7,465 | |
| 1916 | D | 2,089 | 1,762 | 3,906 | |
| 1912 | D | 1,931 | 520 | 3,650 | |
| 1908 | D | 2,356 | 1,903 | 4,332 | |
| 1904 | D | 2,142 | 2,105 | 4,306 | |
| 1900 | D | 2,278 | 2,078 | 4,403 | |
| 1896 | R | 2,109 | 2,139 | 4,283 | |
| 1892 | D | 2,074 | 1,890 | 4,084 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Perry County sits along the Ohio River in southern Indiana, and its roughly 19,000 residents have shifted steadily toward Republican presidential candidates over the past decade, reaching a nearly 30-point margin in 2024.
The county's recent history is a story of close margins. The Democratic margin reached thirty-nine points in 1912; the Republican margin reached thirty points in 2024. Most other elections have been decided by single-digit points.
Perry County's demographics — a population of 19,270, a 93% non-Hispanic-white share, a median household income of $61,151 — situate the county close to national averages on several dimensions. The county's voting pattern over the last decade is most similar to that of Adams County and Manistee County.