| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 1,000 | 2,551 | 3,615 | |
| 2020 | R | 1,177 | 2,552 | 3,783 | |
| 2016 | R | 935 | 2,382 | 3,433 | |
| 2012 | R | 1,483 | 2,230 | 3,764 | |
| 2008 | R | 1,807 | 2,109 | 3,978 | |
| 2004 | R | 2,155 | 2,556 | 4,798 | |
| 2000 | D | 2,205 | 1,300 | 3,579 | |
| 1996 | D | 1,913 | 1,711 | 4,035 | |
| 1992 | D | 1,639 | 1,570 | 4,099 | |
| 1988 | D | 2,205 | 1,966 | 4,184 | |
| 1984 | R | 1,879 | 2,660 | 4,563 | |
| 1980 | R | 1,741 | 2,608 | 4,599 | |
| 1976 | D | 2,593 | 1,779 | 4,394 | |
| 1972 | D | 2,691 | 2,020 | 4,721 | |
| 1968 | D | 2,369 | 2,093 | 4,675 | |
| 1964 | D | 3,488 | 1,625 | 5,113 | |
| 1960 | D | 2,754 | 2,446 | 5,200 | |
| 1956 | D | 3,117 | 2,202 | 5,319 | |
| 1952 | R | 2,790 | 3,316 | 6,106 | |
| 1948 | D | 3,086 | 1,800 | 4,935 | |
| 1944 | D | 2,701 | 2,171 | 4,872 | |
| 1940 | D | 3,303 | 2,993 | 6,296 | |
| 1936 | D | 4,628 | 2,209 | 6,912 | |
| 1932 | D | 5,399 | 1,397 | 6,846 | |
| 1928 | R | 3,039 | 3,087 | 6,140 | |
| 1924 | R | 1,306 | 1,680 | 5,382 | |
| 1920 | R | 1,305 | 2,021 | 4,028 | |
| 1916 | R | 1,450 | 2,011 | 3,514 | |
| 1912 | D | 1,625 | 0 | 3,545 | |
| 1908 | R | 1,391 | 1,863 | 3,334 | |
| 1904 | R | 823 | 1,765 | 2,722 | |
| 1900 | R | 1,058 | 1,108 | 2,197 | |
| 1896 | R | 594 | 698 | 1,303 | |
| 1892 | R | 115 | 516 | 899 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Charles Mix sits along the Missouri River and includes the Yankton Sioux Reservation, giving it one of South Dakota's more demographically complex electorates despite its small population — yet Republican presidential margins have exceeded 40 points in recent cycles.
The Republican margin in Charles Mix County reached its widest at forty-five points in 1892. The margin in 2024 was forty-three points, in line with the county's deep historical pattern.
Charles Mix County's loyalty is rooted in its place. Median household income of $64,038, a 64% non-Hispanic-white share, and a population of 9,281 together describe a community whose political habits are deeply settled. The county's voting pattern over the last decade is most similar to that of McCook County and Yancey County.
