| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | D | 4,505 | 3,078 | 8,076 | |
| 2020 | D | 5,329 | 3,008 | 8,431 | |
| 2016 | D | 5,199 | 2,803 | 8,156 | |
| 2012 | D | 5,977 | 2,832 | 8,907 | |
| 2008 | D | 5,960 | 3,074 | 9,153 | |
| 2004 | D | 4,960 | 2,901 | 7,898 | |
| 2000 | D | 3,899 | 2,675 | 6,642 | |
| 1996 | D | 3,588 | 1,973 | 5,908 | |
| 1992 | D | 4,454 | 2,730 | 7,822 | |
| 1988 | D | 3,423 | 2,936 | 6,359 | |
| 1984 | D | 3,912 | 3,548 | 7,500 | |
| 1980 | D | 4,818 | 2,952 | 7,877 | |
| 1976 | D | 3,869 | 2,357 | 6,254 | |
| 1972 | R | 1,996 | 3,076 | 5,100 | |
| 1968 | D | 2,151 | 1,219 | 5,483 | |
| 1964 | R | 1,156 | 2,489 | 3,645 | |
| 1960 | D | 1,487 | 1,297 | 2,784 | |
| 1956 | D | 943 | 250 | 2,465 | |
| 1952 | R | 927 | 1,669 | 2,596 | |
| 1948 | D | 142 | 36 | 1,333 | |
| 1944 | D | 764 | 50 | 875 | |
| 1940 | D | 825 | 20 | 845 | |
| 1936 | D | 1,045 | 0 | 1,050 | |
| 1932 | D | 742 | 0 | 752 | |
| 1928 | D | 593 | 6 | 599 | |
| 1924 | — | 0 | 0 | 0 | |
| 1920 | D | 734 | 18 | 754 | |
| 1916 | D | 779 | 14 | 806 | |
| 1912 | D | 571 | 0 | 580 | |
| 1908 | D | 963 | 58 | 1,023 | |
| 1904 | D | 1,128 | 13 | 1,141 | |
| 1900 | — | — | — | — | |
| 1896 | — | — | — | — | |
| 1892 | — | — | — | — | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Lee County's electorate is majority Black, anchoring consistent double-digit Democratic margins even as rural counties across the South have trended sharply Republican over the past two decades.
The Democratic margin in Lee County peaked at 100 points in 1936. By 1976 the county had flipped, voting Republican for the first time in many years. The 2024 margin was eighteen points, the most Democratic-leaning result in the county's modern history.
The economic context is the key. Lee County's median household income of $44,760 sits well below state and national norms, and 25% of residents live below the federal poverty line. The shift here is part of a broader realignment of working-class places across the country. The county's voting pattern over the last decade is most similar to that of Williamsburg County and Orangeburg County.